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Research Associate I - Smidt Heart Institute - Karlstaedt Lab

Company: Cedars-Sinai
Location: Los Angeles
Posted on: November 22, 2021

Job Description:

Dr. Anja Karlstaedt's laboratory is looking for a highly motivated Research Associate I interested in the metabolic crosstalk between cardiac and cancer cells to join the Department of Cardiology within the Smidt Heart Institute at Cedars-Sinai Medical Center! Cedars-Sinai is a multidisciplinary, highly collaborative research center with an emphasis on disease and translational research.

Dr. Karlstaedt's research focuses on the cellular mechanisms that cause heart failure in cancer patients using interdisciplinary and computational approaches. Our work has uncovered several regulatory mechanisms that explain how oncometabolic stress induces metabolic and proteomic remodeling in the heart and skeletal muscle. The challenge is now to develop strategies that target the tumor while protecting the heart.

We are looking for a highly motivated and creative scientist with a basic scientific background who is willing to learn new techniques, collaborate with postdoctoral scientists, and excited about the challenges of examining the interactions between metabolism, cancer, and immunity

Working under direct supervision, you will perform a variety of routine experimental protocols and procedures to support the objectives of one or more laboratory research projects in a specific area of research. Assists in general laboratory activities, including maintenance of reagents and stocking of supplies. Files and monitors documents. Keeps accurate and detailed records of experiments and results. Assists in the operation of specialized equipment and machinery. Observes safety standards and procedures. You will be able to perform routine cellular, micro- and molecular biology procedures including, but not limited to Western, Northern blot, DNA/RNA, PCR, protein extraction, cell culture, Immunohistochemistry, and staining. This position does not have supervisory responsibilities.

Essential job duties and responsibilities:

  • Independently conduct experiments planned together with the PI.
  • Maintain accurate, complete, up-to-date notes about lab work and results.
  • Willingness to learn new techniques and an ability to follow protocol instructions.
  • Analyze basic data sets and generate figures.
  • Participate in regular lab meetings.
  • Performs a variety of routine laboratory tasks and procedures.
  • Keeps accurate and detailed project records of experiments and results.
  • May assist with animal husbandry.
  • Maintains lab equipment and related records.
  • Transports, processes and logs samples.
  • Maintains computer database with relevant clinical information.
  • Performs lab maintenance duties, including glassware cleaning and sterilization.
  • Maintains stocks of general lab materials, and places orders for lab equipment and supplies.
  • Observes and complies with safety standards and procedures.

    Educational Requirements
    • Bachelor of Science or Bachelor of Arts Degree in Biological Sciences is required
      Experience:
      • Understanding of general research objectives.
      • Working knowledge of database management, personal computers, and presentation and imaging software.
      • Understanding of general research objectives.
      • Familiar with routine laboratory procedures and experimental protocols.
      • Must possess computer skills to include, but not limited to, Excel and Word.
      • Some experience with some basic molecular biology techniques is an advantage (e.g., ELISA, Western Blots, protein assays, cloning, RNA and DNA isolation).
      • Prior basic experience with cell culture is desirable.
      • Coordination of tasks and activities to maximize the effectiveness of time management
      • Additional programming experiences in R, python or perl is preferred

Keywords: Cedars-Sinai, Los Angeles , Research Associate I - Smidt Heart Institute - Karlstaedt Lab, Healthcare , Los Angeles, California

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